Fenoxycarb, An Insect Growth Regulator (IGR), Induces Anemia In Mammals
Price
Free (open access)
Transaction
Volume
14
Pages
12
Published
1996
Size
983 kb
Paper DOI
10.2495/AIR960381
Copyright
WIT Press
Author(s)
A.A. Bazzaz
Abstract
Fenoxycarb, an Insect growth regulator (IGR), has been investigated to determine its toxic effect on mammalian life by analyzing blood samples as an indicator. One hundred and eight male mice were used in this study (24 control and 84 experimental animals). The mice were sacrificed by head dislocation, and blood samples were collected into heparinised tubes for haematological tests. Haematological changes in blood parameters have been measured in mice given fenoxycarb in water at three different dose (1, 5 and 10 ppm) for 4 weeks. Fenoxycarb primarily induced a mild to moderate anemia as early as the first week, at all three doses by causing a significant (p<0.05-0.0001) decline in the levels of haemoglobin (Hb%), packed cell volume (PCV%) leucocytesKeywords