Effects Of Tumour-induced Flow Patterns On Aerosol Drug Delivery
Price
Free (open access)
Transaction
Volume
4
Pages
10
Published
1997
Size
813 kb
Paper DOI
10.2495/BIO970131
Copyright
WIT Press
Author(s)
X. Guan & T.B. Martonen
Abstract
This manuscript presents a theoretical study of fluid dynamics in diseased lungs. The objective was to describe fluid behavior and assist in the development of new techniques for targeted delivery of drugs. Numerical simulations were conducted using FIDAP on the Cray T90 supercomputer. Two lung bifurcations with tumors in tracheobronchial airways were considered. Weibel [1] lung morphology and Hofmann et al. [2] breathing parameters were employed. It has been observed that the effects of tumor size, rat
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