Author(s)

P.R. Johnston & D. Kilpatrick

Abstract

A transient analysis of human coronary artery blood flow P.R. Johnston & D. Kilpatrick Department of Medicine, University of Tasmania, Cof/ma 6Y., #o6orf, Toamom'o 7000, ABSTRACT Despite its prevalence, little is known about the initiating factors for coro- nary artery disease. Physical factors associated with blood flow have been implicated with some believing that regions of low wall shear stress pre- dispose to atheroma and subsequent narrowing, but others believe that narrowing is initiated by high shear stress. This paper presents a modelling study of blood flowing through the first main junction in the left side of the human coronary artery tree, involving the left main stem, the left anterior descending (LAD) and the left cir- cumflex arteries (LCA). The eventual aim is to find a correlation between regions of calculated high and low wall shear stress and the position of arterial narrowing. The paper presents results of transient and steady s

Keywords