Biomedical Application Of The Supercomputer: Targeted Delivery Of Inhaled Pharmaceuticals In Diseased Lungs
Price
Free (open access)
Transaction
Volume
2
Pages
8
Published
1995
Size
585 kb
Paper DOI
10.2495/BIO950291
Copyright
WIT Press
Author(s)
T.B. Martonen, I. Katz, D. Hwang & Y. Yang
Abstract
The primary pathological manifestation of cystic fibrosis (CF) is the ob- struction of biological passages throughout the body by mucus. However, all patients will develop chronic obstructive lung disease which accounts for more than 90% of CF mortality. We have used the Cray Y-MP to develop a mathematical model for targeting the delivery of inhaled pharmacologic drugs in the treatment of respir
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